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Chunji YAN, Maozhao XIE,
《能源前沿(英文)》 2010年 第4卷 第2期 页码 198-204 doi: 10.1007/s11708-009-0054-5
关键词: liquid jet dominant wave number compressibility instability
Time reversal method for guided wave inspection in pipes
DENG Fei, WU Bin, HE Cunfu
《机械工程前沿(英文)》 2008年 第3卷 第3期 页码 251-260 doi: 10.1007/s11465-008-0050-1
关键词: reversal process beneficial circumferential location energy number
null
《医学前沿(英文)》 2016年 第10卷 第3期 页码 311-319 doi: 10.1007/s11684-016-0460-0
We evaluated the roles of calpain cleavage-related mutations of the integrin β3 cytoplasmic tail in integrin αIIbβ3 bidirectional signaling using a trans-dominant inhibition model. Chimeric Tac-β3 proteins (i.e., Tac-β3, Tac-β3D741, Tac-β3D747, Tac-β3D754, Tac-β3D759, and Tac-β3DNITY) consisting of the extracellular and transmembrane domains of human IL-2 receptor (Tac) and the human integrin β3 cytoplasmic domain were stably expressed in the 123 CHO cells harboring human glycoprotein Ib-IX and wild-type integrin αIIbβ3. The different cells were assayed for stable adhesion and spreading on immobilized fibrinogen, and for binding soluble fibrinogen representing outside-in and inside-out signaling events, respectively. The chimeric protein Tac-β3 inhibited, and Tac-β3DNITY partially attenuated stable adhesion and spreading. Tac-β3, Tac-β3D759, Tac-β3DNITY, and Tac-β3D754, but not Tac-β3D747 or Tac-β3D741, impaired the soluble fibrinogen binding. Results indicated that the bidirectional signaling was significantly inhibited by Tac-β3 and Tac-β3DNITY, albeit to a much lesser extent. Moreover, only inside-out signaling was impaired in the 123/Tac-β3D759 and 123/Tac-β3D754 cells in contrast to an intact bidirectional signaling in the 123/Tac-β3D747 and 123/Tac-β3D741 cells. In conclusion, the calpain cleavage of integrin β3 resulted in the regulatory effects on signaling by interrupting its interaction with cytoplasmic proteins rather than altering its conformation, and may thus regulate platelet function.
关键词: integrin β3 signal transduction trans-dominant inhibition model
Jiuxiao Hao, Xiujin Wang, Hui Wang
《环境科学与工程前沿(英文)》 2017年 第11卷 第1期 doi: 10.1007/s11783-017-0896-8
关键词: Polyhydroxyalkanoates (PHAs) Valerate Mixed culture 3-hydroxyvalerate (3HV) Propionate
YANG Shengxiang,LIANG Shichu,YI Langbo,XU Bibo,CAO Jianbing,GUO Yifeng,ZHOU Yu
《环境科学与工程前沿(英文)》 2014年 第8卷 第3期 页码 394-404 doi: 10.1007/s11783-013-0602-4
关键词: Mn mine tailings heavy metal accumulation phytostabilization
《医学前沿(英文)》 2022年 第16卷 第5期 页码 773-783 doi: 10.1007/s11684-021-0902-1
关键词: benefit China eligibility immune checkpoint inhibitor public health
Ali KARIMPOUR, Salam RAHMATALLA
《结构与土木工程前沿(英文)》 2020年 第14卷 第6期 页码 1331-1348 doi: 10.1007/s11709-020-0686-4
关键词: structural model validation eigenvalue problem response surface inverse problems
Study on wave rotor refrigerators
Yuqiang DAI, Dapeng HU, Meixia DING
《化学科学与工程前沿(英文)》 2009年 第3卷 第1期 页码 83-87 doi: 10.1007/s11705-009-0075-y
关键词: wave rotor refrigeration unsteady flow theory wave diagram
Prediction of the shear wave velocity
Amoroso SARA
《结构与土木工程前沿(英文)》 2014年 第8卷 第1期 页码 83-92 doi: 10.1007/s11709-013-0234-6
关键词: horizontal stress index shear wave velocity flat dilatometer test cone penetration test
Lamb wave propagation modeling for structure health monitoring
Xiaoyue ZHANG, Shenfang YUAN, Tong HAO
《机械工程前沿(英文)》 2009年 第4卷 第3期 页码 326-331 doi: 10.1007/s11465-009-0045-6
关键词: Lamb wave modeling LISA/SIM theory finite difference equation finite element
Hydrogen production by catalytic gasification of cellulose in supercritical water
GUAN Yu, PEI Aixia, GUO Liejin
《化学科学与工程前沿(英文)》 2008年 第2卷 第2期 页码 176-180 doi: 10.1007/s11705-008-0026-z
关键词: reaction temperature combination catalytic effect dominant product
Forecast method for used number of parts and components based on complex network
LIU Fu-yun, QI Guo-ning, YANG Qing-hai
《机械工程前沿(英文)》 2006年 第1卷 第4期 页码 479-484 doi: 10.1007/s11465-006-0064-5
关键词: complex network industrial component analytic expression forecast
Wu YU, Gen CHEN, Zuohua HUANG
《能源前沿(英文)》 2011年 第5卷 第4期 页码 412-418 doi: 10.1007/s11708-011-0163-9
关键词: biodiesel methanol common-rail (CR) diesel engine cetane number (CN) improver
Simulation of cross-flow-induced vibration of tube bundle by surface vorticity method
WANG Fenghao, JIANG Gedong, Lin John Zhang
《能源前沿(英文)》 2008年 第2卷 第3期 页码 243-248 doi: 10.1007/s11708-008-0049-7
关键词: dominant sub-critical Reynolds staggered Vorticity three-row
Junqin PANG, Masami MATSUDA, Masashi KURODA, Daisuke INOUE, Kazunari SEI, Kei NISHIDA, Michihiko IKE
《环境科学与工程前沿(英文)》 2016年 第10卷 第4期 doi: 10.1007/s11783-016-0846-x
关键词: DNA microarray analysis Nitrogen cycling functional genes Most probable number-polymerase chain reaction (MPN-PCR) Wastewater treatment plants (WWTPs)
标题 作者 时间 类型 操作
Stability of an annular viscous liquid jet in compressible gases with different properties inside and outside of the jet
Chunji YAN, Maozhao XIE,
期刊论文
Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition
null
期刊论文
Investigation of polyhydroxyalkanoates (PHAs) biosynthesis from mixed culture enriched by valerate-dominant
Jiuxiao Hao, Xiujin Wang, Hui Wang
期刊论文
Heavy metal accumulation and phytostabilization potential of dominant plant species growing on manganese
YANG Shengxiang,LIANG Shichu,YI Langbo,XU Bibo,CAO Jianbing,GUO Yifeng,ZHOU Yu
期刊论文
Estimating the number of Chinese cancer patients eligible for and benefit from immune checkpoint inhibitors
期刊论文
Identification of structural parameters and boundary conditions using a minimum number of measurement
Ali KARIMPOUR, Salam RAHMATALLA
期刊论文
Lamb wave propagation modeling for structure health monitoring
Xiaoyue ZHANG, Shenfang YUAN, Tong HAO
期刊论文
Hydrogen production by catalytic gasification of cellulose in supercritical water
GUAN Yu, PEI Aixia, GUO Liejin
期刊论文
Forecast method for used number of parts and components based on complex network
LIU Fu-yun, QI Guo-ning, YANG Qing-hai
期刊论文
Influence of cetane number improver on performance and emissions of a common-rail diesel engine fueled
Wu YU, Gen CHEN, Zuohua HUANG
期刊论文
Simulation of cross-flow-induced vibration of tube bundle by surface vorticity method
WANG Fenghao, JIANG Gedong, Lin John Zhang
期刊论文